diff --git a/pkgs/development/python-modules/urllib3/2.nix b/pkgs/development/python-modules/urllib3/2.nix
new file mode 100644
index 00000000000..b44993c71b2
--- /dev/null
+++ b/pkgs/development/python-modules/urllib3/2.nix
@@ -0,0 +1,74 @@
+{ lib
+, stdenv
+, brotli
+, buildPythonPackage
+, certifi
+, cryptography
+, dateutil
+, fetchPypi
+, idna
+, mock
+, pyopenssl
+, pysocks
+, pytest-freezegun
+, pytest-timeout
+, pytestCheckHook
+, pythonOlder
+, tornado
+, trustme
+}:
+
+buildPythonPackage rec {
+  pname = "urllib3";
+  version = "1.26.2";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "19188f96923873c92ccb987120ec4acaa12f0461fa9ce5d3d0772bc965a39e08";
+  };
+
+  propagatedBuildInputs = [
+    brotli
+    certifi
+    cryptography
+    idna
+    pyopenssl
+    pysocks
+  ];
+
+  checkInputs = [
+    dateutil
+    mock
+    pytest-freezegun
+    pytest-timeout
+    pytestCheckHook
+    tornado
+    trustme
+  ];
+
+  # Tests in urllib3 are mostly timeout-based instead of event-based and
+  # are therefore inherently flaky. On your own machine, the tests will
+  # typically build fine, but on a loaded cluster such as Hydra random
+  # timeouts will occur.
+  #
+  # The urllib3 test suite has two different timeouts in their test suite
+  # (see `test/__init__.py`):
+  # - SHORT_TIMEOUT
+  # - LONG_TIMEOUT
+  # When CI is in the env, LONG_TIMEOUT will be significantly increased.
+  # Still, failures can occur and for that reason tests are disabled.
+  doCheck = false;
+
+  preCheck = ''
+    export CI # Increases LONG_TIMEOUT
+  '';
+
+  pythonImportsCheck = [ "urllib3" ];
+
+  meta = with lib; {
+    description = "Powerful, sanity-friendly HTTP client for Python";
+    homepage = "https://github.com/shazow/urllib3";
+    license = licenses.mit;
+    maintainers = with maintainers; [ fab ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 7fa21d27541..6c4c0738a6d 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -8524,9 +8524,12 @@ in {
 
   urlgrabber = callPackage ../development/python-modules/urlgrabber { };
 
-  urllib3 = callPackage ../development/python-modules/urllib3 {
-    pytestCheckHook = self.pytestCheckHook_6_1;
-  };
+  urllib3 = if isPy3k then
+    callPackage ../development/python-modules/urllib3 {
+      pytestCheckHook = self.pytestCheckHook_6_1;
+    }
+  else
+    callPackage ../development/python-modules/urllib3/2.nix { };
 
   urwid = callPackage ../development/python-modules/urwid { };