diff --git a/pkgs/desktops/gnome-2/bindings/gnome-python/default.nix b/pkgs/desktops/gnome-2/bindings/gnome-python/default.nix
deleted file mode 100644
index 0c636ffa541..00000000000
--- a/pkgs/desktops/gnome-2/bindings/gnome-python/default.nix
+++ /dev/null
@@ -1,33 +0,0 @@
-{ lib, stdenv, fetchurl, python2, pkg-config, libgnome, GConf, glib, gtk2, gnome_vfs }:
-
-with lib;
-
-let
-  inherit (python2.pkgs) python pygobject2 pygtk dbus-python;
-in stdenv.mkDerivation rec {
-  pname = "gnome-python";
-  version = "2.28.1";
-
-  src = fetchurl {
-    url = "mirror://gnome/sources/gnome-python/${lib.versions.majorMinor version}/gnome-python-${version}.tar.bz2";
-    sha256 = "759ce9344cbf89cf7f8449d945822a0c9f317a494f56787782a901e4119b96d8";
-  };
-
-  nativeBuildInputs = [ pkg-config ];
-  buildInputs = [ python glib gtk2 GConf libgnome gnome_vfs ];
-  propagatedBuildInputs = [ pygobject2 pygtk dbus-python ];
-
-  # gnome-python expects that .pth file is already installed by PyGTK in the
-  # same directory. This is not the case for Nix.
-  postInstall = ''
-    echo "gtk-2.0" > $out/${python2.sitePackages}/gnome-python-${version}.pth
-  '';
-
-  meta = with lib; {
-    homepage = "http://pygtk.org/";
-    description = "Python wrapper for GNOME libraries";
-    platforms = platforms.linux;
-    license = licenses.lgpl2;
-    maintainers = with maintainers; [ qknight ];
-  };
-}
diff --git a/pkgs/desktops/gnome-2/default.nix b/pkgs/desktops/gnome-2/default.nix
index 75ef97817c3..3dfcc519097 100644
--- a/pkgs/desktops/gnome-2/default.nix
+++ b/pkgs/desktops/gnome-2/default.nix
@@ -33,8 +33,6 @@ lib.makeScope pkgs.newScope (self: with self; {
 
   gnome_mime_data = callPackage ./platform/gnome-mime-data { };
 
-  gnome_python = callPackage ./bindings/gnome-python { };
-
   gnome_vfs = callPackage ./platform/gnome-vfs { };
 
   libgnome = callPackage ./platform/libgnome { };
@@ -79,6 +77,7 @@ lib.makeScope pkgs.newScope (self: with self; {
   gnome_icon_theme = self.gnome-icon-theme;
   gnomeicontheme = self.gnome-icon-theme;
   gnome_common = gnome-common;
+  gnome_python = throw "gnome2.gnome_python has been removed"; # 2023-01-14
   gnome_python_desktop = throw "gnome2.gnome_python_desktop has been removed"; # 2023-01-14
   libglademm = throw "gnome2.libglademm has been removed"; # 2022-01-15
   python_rsvg = throw "gnome2.python_rsvg has been removed"; # 2023-01-14