diff --git a/pkgs/development/ocaml-modules/lwt/default.nix b/pkgs/development/ocaml-modules/lwt/default.nix
index 8004cfcd4bb..cf631fd08e4 100644
--- a/pkgs/development/ocaml-modules/lwt/default.nix
+++ b/pkgs/development/ocaml-modules/lwt/default.nix
@@ -1,5 +1,5 @@
 { lib, fetchFromGitHub, libev, buildDunePackage
-, cppo, dune-configurator, ocplib-endian
+, ocaml, cppo, dune-configurator, ocplib-endian
 }:
 
 buildDunePackage rec {
@@ -15,6 +15,11 @@ buildDunePackage rec {
     sha256 = "sha256-XstKs0tMwliCyXnP0Vzi5WC27HKJGnATUYtbbQmH1TE=";
   };
 
+  postPatch = lib.optionalString (lib.versionAtLeast ocaml.version "5.0") ''
+    substituteInPlace src/unix/dune \
+      --replace "libraries bigarray lwt" "libraries lwt"
+  '';
+
   nativeBuildInputs = [ cppo ];
   buildInputs = [ dune-configurator ];
   propagatedBuildInputs = [ libev ocplib-endian ];