diff --git a/pkgs/development/python-modules/notmuch/2.nix b/pkgs/development/python-modules/notmuch/2.nix
new file mode 100644
index 00000000000..593eed6c251
--- /dev/null
+++ b/pkgs/development/python-modules/notmuch/2.nix
@@ -0,0 +1,22 @@
+{ stdenv
+, buildPythonPackage
+, notmuch
+, python
+, cffi
+}:
+
+buildPythonPackage {
+  pname = "notmuch2";
+  inherit (notmuch) version src;
+
+  sourceRoot = "${notmuch.src.name}/bindings/python-cffi";
+
+  buildInputs = [ python notmuch cffi ];
+
+  meta = with stdenv.lib; {
+    description = "Pythonic bindings for the notmuch mail database using CFFI";
+    homepage = "https://notmuchmail.org/";
+    license = licenses.gpl3;
+    maintainers = with maintainers; [ teto ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 51ae93b0eb1..d9862a193e4 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -4140,6 +4140,7 @@ in {
   notify-py = callPackage ../development/python-modules/notify-py { };
 
   notmuch = callPackage ../development/python-modules/notmuch { inherit (pkgs) notmuch; };
+  notmuch2 = callPackage ../development/python-modules/notmuch/2.nix { inherit (pkgs) notmuch; };
 
   nototools = callPackage ../data/fonts/noto-fonts/tools.nix { };