diff --git a/pkgs/development/python-modules/pylibftdi/default.nix b/pkgs/development/python-modules/pylibftdi/default.nix
new file mode 100644
index 00000000000..9e8f96665d0
--- /dev/null
+++ b/pkgs/development/python-modules/pylibftdi/default.nix
@@ -0,0 +1,38 @@
+{ lib
+, buildPythonPackage
+, fetchPypi
+, httpserver
+, libftdi1
+, libusb1
+}:
+
+buildPythonPackage rec {
+  pname = "pylibftdi";
+  version = "0.18.1";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "17c5h4xz1grynbpffngjflk3dlw2g2zbhkwb7h5v4n9rjdv41l5x";
+  };
+
+  propagatedBuildInputs = [
+    httpserver
+    libftdi1
+    libusb1
+  ];
+
+  postPatch = ''
+    substituteInPlace pylibftdi/driver.py \
+      --replace "self._load_library('libusb')" "cdll.LoadLibrary('${libusb1.out}/lib/libusb1.so')" \
+      --replace "self._load_library('libftdi')" "cdll.LoadLibrary('${libftdi1.out}/lib/libftdi1.so')"
+  '';
+
+  pythonImportsCheck = [ "pylibftdi" ];
+
+  meta = with lib; {
+    homepage = "https://bitbucket.org/codedstructure/pylibftdi/src/default/";
+    description = "Minimal pythonic wrapper to Intra2net's libftdi driver for FTDI's USB devices";
+    license = licenses.mit;
+    maintainers = with maintainers; [ matthuszagh ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 68debd34013..755c724e275 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -1222,6 +1222,10 @@ in {
 
   pylev = callPackage ../development/python-modules/pylev { };
 
+  pylibftdi = callPackage ../development/python-modules/pylibftdi {
+    inherit (pkgs) libusb1;
+  };
+
   pymatgen = callPackage ../development/python-modules/pymatgen { };
 
   pymatgen-lammps = callPackage ../development/python-modules/pymatgen-lammps { };