diff --git a/pkgs/development/python-modules/pyperscan/default.nix b/pkgs/development/python-modules/pyperscan/default.nix
new file mode 100644
index 00000000000..954da379d7e
--- /dev/null
+++ b/pkgs/development/python-modules/pyperscan/default.nix
@@ -0,0 +1,51 @@
+{ lib
+, stdenv
+, fetchFromGitHub
+, buildPythonPackage
+, rustPlatform
+, pytestCheckHook
+, libiconv
+, vectorscan
+}:
+
+buildPythonPackage rec {
+  pname = "pyperscan";
+  version = "0.2.2";
+  format = "pyproject";
+
+  src = fetchFromGitHub {
+    owner = "vlaci";
+    repo = "pyperscan";
+    rev = "v${version}";
+    hash = "sha256-ioNGEmWy+lEzazF1RzMFS06jYLNYll3QSlWAF0AoU7Y=";
+  };
+
+  cargoDeps = rustPlatform.fetchCargoTarball {
+    inherit src;
+    name = "${pname}-${version}";
+    hash = "sha256-2zppyxJ+XaI/JCkp7s27/jgtSbwxnI4Yil5KT8WgrVI=";
+  };
+
+  nativeBuildInputs = with rustPlatform; [
+    bindgenHook
+    cargoSetupHook
+    maturinBuildHook
+  ];
+
+  checkInputs = [ pytestCheckHook ];
+
+  buildInputs = [ vectorscan ] ++ lib.optional stdenv.isDarwin libiconv;
+
+  # Disable default features to use the system vectorscan library instead of a vendored one.
+  maturinBuildFlags = [ "--no-default-features" ];
+
+  pythonImportsCheck = [ "pyperscan" ];
+
+  meta = with lib; {
+    description = "a hyperscan binding for Python, which supports vectorscan";
+    homepage = "https://github.com/vlaci/pyperscan";
+    platforms = platforms.unix;
+    license = with licenses; [ asl20 /* or */ mit ];
+    maintainers = with maintainers; [ tnias vlaci ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 54e54745870..c06077e3c34 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -8971,6 +8971,8 @@ self: super: with self; {
 
   pyperclip = callPackage ../development/python-modules/pyperclip { };
 
+  pyperscan = callPackage ../development/python-modules/pyperscan { };
+
   pyperf = callPackage ../development/python-modules/pyperf { };
 
   pyphen = callPackage ../development/python-modules/pyphen { };