diff --git a/pkgs/development/python-modules/anyio/default.nix b/pkgs/development/python-modules/anyio/default.nix
index 516b8520f00..f79bf23896f 100644
--- a/pkgs/development/python-modules/anyio/default.nix
+++ b/pkgs/development/python-modules/anyio/default.nix
@@ -1,4 +1,5 @@
-{ lib
+{ stdenv
+, lib
 , buildPythonPackage
 , fetchFromGitHub
 , pythonOlder
@@ -45,6 +46,9 @@ buildPythonPackage rec {
   pytestFlagsArray = [
     # lots of DNS lookups
     "--ignore=tests/test_sockets.py"
+  ] ++ lib.optionals stdenv.isDarwin [
+    # darwin sandboxing limitations
+    "--ignore=tests/streams/test_tls.py"
   ];
 
   pythonImportsCheck = [ "anyio" ];