diff --git a/pkgs/development/python-modules/psycopg2cffi/default.nix b/pkgs/development/python-modules/psycopg2cffi/default.nix
new file mode 100644
index 00000000000..71c9017380a
--- /dev/null
+++ b/pkgs/development/python-modules/psycopg2cffi/default.nix
@@ -0,0 +1,39 @@
+{ buildPythonPackage, cffi, fetchFromGitHub, lib, postgresql, pytestCheckHook, six }:
+
+buildPythonPackage rec {
+  pname = "psycopg2cffi";
+  version = "2.8.1";
+
+  # NB: This is a fork.
+  # The original repo exists at https://github.com/chtd/psycopg2cffi, however
+  # this is mostly unmaintained and does not build for PyPy. Given that the
+  # whole point of this cffi alternative to psycopg2 is to use it with PyPy, I
+  # chose to use a working fork instead, which was linked in the relevant issue:
+  # https://github.com/chtd/psycopg2cffi/issues/113#issuecomment-730548574
+  #
+  # If/when these changes get merged back upstream we should revert to using the
+  # original source as opposed to the fork.
+  src = fetchFromGitHub {
+    owner = "Omegapol";
+    repo = pname;
+    rev = "c202b25cd861d5e8f0f55c329764ff1da9f020c0";
+    sha256 = "09hsnjkix1c0vlhmfvrp8pchpnz2ya4xrchyq15czj527nx2dmy2";
+  };
+
+  nativeBuildInputs = [ postgresql ];
+  propagatedBuildInputs = [ six cffi ];
+  checkInputs = [ pytestCheckHook ];
+
+  # NB: The tests need a postgres instance running to test against, and so we
+  # disable them.
+  doCheck = false;
+
+  pythonImportsCheck = [ "psycopg2cffi" ];
+
+  meta = with lib; {
+    description = "An implementation of the psycopg2 module using cffi";
+    homepage = "https://pypi.org/project/psycopg2cffi/";
+    license = with licenses; [ lgpl3Plus ];
+    maintainers = with maintainers; [ lovesegfault ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 099fd106d2a..125c27dcde8 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -4779,6 +4779,8 @@ in {
 
   psycopg2 = callPackage ../development/python-modules/psycopg2 { };
 
+  psycopg2cffi = callPackage ../development/python-modules/psycopg2cffi { };
+
   ptable = callPackage ../development/python-modules/ptable { };
 
   ptest = callPackage ../development/python-modules/ptest { };