diff --git a/pkgs/development/python-modules/matplotlib/default.nix b/pkgs/development/python-modules/matplotlib/default.nix
index 79c842f6d3e..a033e8a11ba 100644
--- a/pkgs/development/python-modules/matplotlib/default.nix
+++ b/pkgs/development/python-modules/matplotlib/default.nix
@@ -45,6 +45,11 @@ buildPythonPackage rec {
     Cocoa
   ];
 
+  # clang-11: error: argument unused during compilation: '-fno-strict-overflow' [-Werror,-Wunused-command-line-argument]
+  hardeningDisable = lib.optionals stdenv.isDarwin [
+    "strictoverflow"
+  ];
+
   propagatedBuildInputs = [
     certifi
     contourpy