diff --git a/pkgs/development/libraries/libiio/default.nix b/pkgs/development/libraries/libiio/default.nix
index d217fbd8238..98ca22d2e90 100644
--- a/pkgs/development/libraries/libiio/default.nix
+++ b/pkgs/development/libraries/libiio/default.nix
@@ -4,7 +4,7 @@
 , flex
 , bison
 , libxml2
-, python
+, pythonSupport ? stdenv.hostPlatform.hasSharedLibraries, python
 , libusb1
 , avahiSupport ? true, avahi
 , libaio
@@ -19,7 +19,8 @@ stdenv.mkDerivation rec {
   pname = "libiio";
   version = "0.24";
 
-  outputs = [ "out" "lib" "dev" "python" ];
+  outputs = [ "out" "lib" "dev" ]
+    ++ lib.optional pythonSupport "python";
 
   src = fetchFromGitHub {
     owner = "analogdevicesinc";
@@ -37,8 +38,9 @@ stdenv.mkDerivation rec {
     flex
     bison
     pkg-config
+  ] ++ lib.optionals pythonSupport ([
     python
-  ] ++ lib.optional python.isPy3k python.pkgs.setuptools;
+  ] ++ lib.optional python.isPy3k python.pkgs.setuptools);
 
   buildInputs = [
     libxml2
@@ -49,25 +51,26 @@ stdenv.mkDerivation rec {
 
   cmakeFlags = [
     "-DUDEV_RULES_INSTALL_DIR=${placeholder "out"}/lib/udev/rules.d"
-    "-DPython_EXECUTABLE=${python.pythonForBuild.interpreter}"
-    "-DPYTHON_BINDINGS=on"
     # osx framework is disabled,
     # the linux-like directory structure is used for proper output splitting
     "-DOSX_PACKAGE=off"
     "-DOSX_FRAMEWORK=off"
+  ] ++ lib.optionals pythonSupport [
+    "-DPython_EXECUTABLE=${python.pythonForBuild.interpreter}"
+    "-DPYTHON_BINDINGS=on"
   ] ++ lib.optionals (!avahiSupport) [
     "-DHAVE_DNS_SD=OFF"
   ];
 
   postPatch = ''
-    # Hardcode path to the shared library into the bindings.
-    sed "s#@libiio@#$lib/lib/libiio${stdenv.hostPlatform.extensions.sharedLibrary}#g" ${./hardcode-library-path.patch} | patch -p1
-
     substituteInPlace libiio.rules.cmakein \
       --replace /bin/sh ${runtimeShell}
+  '' + lib.optionalString pythonSupport ''
+    # Hardcode path to the shared library into the bindings.
+    sed "s#@libiio@#$lib/lib/libiio${stdenv.hostPlatform.extensions.sharedLibrary}#g" ${./hardcode-library-path.patch} | patch -p1
   '';
 
-  postInstall = ''
+  postInstall = lib.optionalString pythonSupport ''
     # Move Python bindings into a separate output.
     moveToOutput ${python.sitePackages} "$python"
   '';
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index c2572b7a4e7..6d6611eb871 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -5882,7 +5882,10 @@ self: super: with self; {
     inherit (pkgs.config) cudaSupport;
   };
 
-  libiio = (toPythonModule (pkgs.libiio.override { inherit python; })).python;
+  libiio = (toPythonModule (pkgs.libiio.override {
+    pythonSupport = true;
+    inherit python;
+  })).python;
 
   libkeepass = callPackage ../development/python-modules/libkeepass { };