diff --git a/pkgs/development/python-modules/astropy-extension-helpers/default.nix b/pkgs/development/python-modules/astropy-extension-helpers/default.nix
index 90162d431ca..cb15acf8839 100644
--- a/pkgs/development/python-modules/astropy-extension-helpers/default.nix
+++ b/pkgs/development/python-modules/astropy-extension-helpers/default.nix
@@ -35,6 +35,11 @@ buildPythonPackage rec {
     "extension_helpers"
   ];
 
+  disabledTests = [
+    # https://github.com/astropy/extension-helpers/issues/43
+    "test_write_if_different"
+  ];
+
   pythonImportsCheck = [
     "extension_helpers"
   ];