diff --git a/pkgs/development/python-modules/tensorflow/bin.nix b/pkgs/development/python-modules/tensorflow/bin.nix
index 5a35fb8ded4..f5044a360f0 100644
--- a/pkgs/development/python-modules/tensorflow/bin.nix
+++ b/pkgs/development/python-modules/tensorflow/bin.nix
@@ -48,7 +48,8 @@ in buildPythonPackage {
   inherit (packages) version;
   format = "wheel";
 
-  disabled = pythonAtLeast "3.10";
+  # See https://github.com/tensorflow/tensorflow/issues/55581#issuecomment-1101890383
+  disabled = pythonAtLeast "3.10" && !cudaSupport;
 
   src = let
     pyVerNoDot = lib.strings.stringAsChars (x: if x == "." then "" else x) python.pythonVersion;
@@ -97,11 +98,11 @@ in buildPythonPackage {
     (
       cd unpacked/tensorflow*
       # Adjust dependency requirements:
-      # - Relax gast version requirement that doesn't match what we have packaged
+      # - Relax tensorflow-estimator version requirement that doesn't match what we have packaged
       # - The purpose of python3Packages.libclang is not clear at the moment and we don't have it packaged yet
       # - keras and tensorlow-io-gcs-filesystem will be considered as optional for now.
       sed -i *.dist-info/METADATA \
-        -e "s/Requires-Dist: gast.*/Requires-Dist: gast/" \
+        -e "s/Requires-Dist: tf-estimator-nightly.*/Requires-Dist: tensorflow-estimator/" \
         -e "/Requires-Dist: libclang/d" \
         -e "/Requires-Dist: keras/d" \
         -e "/Requires-Dist: tensorflow-io-gcs-filesystem/d"
@@ -177,7 +178,6 @@ in buildPythonPackage {
 
   pythonImportsCheck = [
     "tensorflow"
-    "tensorflow.keras"
     "tensorflow.python"
     "tensorflow.python.framework"
   ];
diff --git a/pkgs/development/python-modules/tensorflow/binary-hashes.nix b/pkgs/development/python-modules/tensorflow/binary-hashes.nix
index 4b2f9d52840..0d221452bb7 100644
--- a/pkgs/development/python-modules/tensorflow/binary-hashes.nix
+++ b/pkgs/development/python-modules/tensorflow/binary-hashes.nix
@@ -1,39 +1,51 @@
 {
-version = "2.7.0";
+version = "2.8.0";
 linux_py_37_cpu = {
-  url = "https://storage.googleapis.com/tensorflow/linux/cpu/tensorflow_cpu-2.7.0-cp37-cp37m-manylinux2010_x86_64.whl";
-  sha256 = "1irw4ri1fbxbj251cnjbr12gxsyj2k30asxjfxjpxhc9b0cchhx0";
+  url = "https://storage.googleapis.com/tensorflow/linux/cpu/tensorflow_cpu-2.8.0-cp37-cp37m-manylinux2010_x86_64.whl";
+  sha256 = "1nza8i0nvqgrcwj2yy74a3wgpgf52svf0yrz9xd6l18gsifkmkx0";
 };
 linux_py_38_cpu = {
-  url = "https://storage.googleapis.com/tensorflow/linux/cpu/tensorflow_cpu-2.7.0-cp38-cp38-manylinux2010_x86_64.whl";
-  sha256 = "11a1rimr998lvvjdg03rqr8h2h7x6bbd4gyv74biwgaxmjczvjdj";
+  url = "https://storage.googleapis.com/tensorflow/linux/cpu/tensorflow_cpu-2.8.0-cp38-cp38-manylinux2010_x86_64.whl";
+  sha256 = "1li2gllznd5w3hh2w9ibh5lkvvssnwh5vhk7i873dxjjdl1w8sqy";
 };
 linux_py_39_cpu = {
-  url = "https://storage.googleapis.com/tensorflow/linux/cpu/tensorflow_cpu-2.7.0-cp39-cp39-manylinux2010_x86_64.whl";
-  sha256 = "0x1zzmgq7hl2k98p8870h0yhaik39nc1ckvxirjx8simpj8ghsbp";
+  url = "https://storage.googleapis.com/tensorflow/linux/cpu/tensorflow_cpu-2.8.0-cp39-cp39-manylinux2010_x86_64.whl";
+  sha256 = "03swmyak1hb0k6b2fi9a8g76fi57jz30ym015a576iwp42pqcgkq";
+};
+linux_py_310_cpu = {
+  url = "https://storage.googleapis.com/tensorflow/linux/cpu/tensorflow_cpu-2.8.0-cp310-cp310-manylinux2010_x86_64.whl";
+  sha256 = "";
 };
 linux_py_37_gpu = {
-  url = "https://storage.googleapis.com/tensorflow/linux/gpu/tensorflow_gpu-2.7.0-cp37-cp37m-manylinux2010_x86_64.whl";
-  sha256 = "1x5yyxzkly9gdyhcfq4x7w7sqqxh6cw5qnfwbvzj5349xwrm63wi";
+  url = "https://storage.googleapis.com/tensorflow/linux/gpu/tensorflow_gpu-2.8.0-cp37-cp37m-manylinux2010_x86_64.whl";
+  sha256 = "06q3vjrlqfkqa5r18hla3d8ms1sqa897g7fpnqizgh4k8skhm9fq";
 };
 linux_py_38_gpu = {
-  url = "https://storage.googleapis.com/tensorflow/linux/gpu/tensorflow_gpu-2.7.0-cp38-cp38-manylinux2010_x86_64.whl";
-  sha256 = "0prxa8yc6lbq62vnh8cw6dhcrnkdjih62kbg6pbw4gmgcbf6v6fg";
+  url = "https://storage.googleapis.com/tensorflow/linux/gpu/tensorflow_gpu-2.8.0-cp38-cp38-manylinux2010_x86_64.whl";
+  sha256 = "0099aa5g19zi74n6bamhmmcgp096m41fhr61swkwnh92myz1ylgb";
 };
 linux_py_39_gpu = {
-  url = "https://storage.googleapis.com/tensorflow/linux/gpu/tensorflow_gpu-2.7.0-cp39-cp39-manylinux2010_x86_64.whl";
-  sha256 = "0jjv8vm20d0airml68bxhassp4yg09rcz2a39aa511cz8mavj0l6";
+  url = "https://storage.googleapis.com/tensorflow/linux/gpu/tensorflow_gpu-2.8.0-cp39-cp39-manylinux2010_x86_64.whl";
+  sha256 = "0zw20yvlqga7znr13pa10qxww42mj64209syiicgvhs74ji1zdca";
+};
+linux_py_310_gpu = {
+  url = "https://storage.googleapis.com/tensorflow/linux/gpu/tensorflow_gpu-2.8.0-cp310-cp310-manylinux2010_x86_64.whl";
+  sha256 = "06kwjlhzl46jhjcg836crys2aw39x0g8s1s9qfscm1kbwzbww1hq";
 };
 mac_py_37_cpu = {
-  url = "https://storage.googleapis.com/tensorflow/mac/cpu/tensorflow-2.7.0-cp37-cp37m-macosx_10_11_x86_64.whl";
-  sha256 = "1gr95ck0h4wzhdacjfhkzxdw4zglm85fc54swqhyzzv1f5n9vw8j";
+  url = "https://storage.googleapis.com/tensorflow/mac/cpu/tensorflow-2.8.0-cp37-cp37m-macosx_10_14_x86_64.whl";
+  sha256 = "1z5w6wx3h45fz0ji9kn2m2kf963bqbvmqc7cyjv4ixymd0rp4jps";
 };
 mac_py_38_cpu = {
-  url = "https://storage.googleapis.com/tensorflow/mac/cpu/tensorflow-2.7.0-cp38-cp38-macosx_10_11_x86_64.whl";
-  sha256 = "1h3qlvlrwyvxynh5flvyqk7grbvyqc21ljqhlvds436hpn2kqrgb";
+  url = "https://storage.googleapis.com/tensorflow/mac/cpu/tensorflow-2.8.0-cp38-cp38-macosx_10_14_x86_64.whl";
+  sha256 = "1h5v8flhc5zb038ld0av7638cyqqkrib379lrlzvf8dw7q8ry3yx";
 };
 mac_py_39_cpu = {
-  url = "https://storage.googleapis.com/tensorflow/mac/cpu/tensorflow-2.7.0-cp39-cp39-macosx_10_11_x86_64.whl";
-  sha256 = "0pyj1p2yik6ysdqn8n6cz1nqni0s9xx51ifmvdx4dl3hrzp86jz2";
+  url = "https://storage.googleapis.com/tensorflow/mac/cpu/tensorflow-2.8.0-cp39-cp39-macosx_10_14_x86_64.whl";
+  sha256 = "0qsmlrf8h2gxkimniyrz9bniaqpdsd92pficmsrq30k8rkz2bwjj";
+};
+mac_py_310_cpu = {
+  url = "https://storage.googleapis.com/tensorflow/mac/cpu/tensorflow-2.8.0-cp310-cp310-macosx_10_14_x86_64.whl";
+  sha256 = "0lnwbvil6c6ai10lcaj9ay9pya207s9g204273msjalm1hpbmhvq";
 };
 }
diff --git a/pkgs/development/python-modules/tensorflow/prefetcher.sh b/pkgs/development/python-modules/tensorflow/prefetcher.sh
index bb189bb06d6..3edc6715827 100755
--- a/pkgs/development/python-modules/tensorflow/prefetcher.sh
+++ b/pkgs/development/python-modules/tensorflow/prefetcher.sh
@@ -1,6 +1,6 @@
 #!/usr/bin/env bash
 
-version="2.7.0"
+version="2.8.0"
 
 bucket="https://storage.googleapis.com/tensorflow"
 
@@ -11,12 +11,15 @@ url_and_key_list=(
 "linux_py_37_cpu $bucket/linux/cpu/tensorflow_cpu-${version}-cp37-cp37m-manylinux2010_x86_64.whl"
 "linux_py_38_cpu $bucket/linux/cpu/tensorflow_cpu-${version}-cp38-cp38-manylinux2010_x86_64.whl"
 "linux_py_39_cpu $bucket/linux/cpu/tensorflow_cpu-${version}-cp39-cp39-manylinux2010_x86_64.whl"
+"linux_py_310_cpu $bucket/linux/cpu/tensorflow_cpu-${version}-cp310-cp310-manylinux2010_x86_64.whl"
 "linux_py_37_gpu $bucket/linux/gpu/tensorflow_gpu-${version}-cp37-cp37m-manylinux2010_x86_64.whl"
 "linux_py_38_gpu $bucket/linux/gpu/tensorflow_gpu-${version}-cp38-cp38-manylinux2010_x86_64.whl"
 "linux_py_39_gpu $bucket/linux/gpu/tensorflow_gpu-${version}-cp39-cp39-manylinux2010_x86_64.whl"
-"mac_py_37_cpu $bucket/mac/cpu/tensorflow-${version}-cp37-cp37m-macosx_10_11_x86_64.whl"
-"mac_py_38_cpu $bucket/mac/cpu/tensorflow-${version}-cp38-cp38-macosx_10_11_x86_64.whl"
-"mac_py_39_cpu $bucket/mac/cpu/tensorflow-${version}-cp39-cp39-macosx_10_11_x86_64.whl"
+"linux_py_310_gpu $bucket/linux/gpu/tensorflow_gpu-${version}-cp310-cp310-manylinux2010_x86_64.whl"
+"mac_py_37_cpu $bucket/mac/cpu/tensorflow-${version}-cp37-cp37m-macosx_10_14_x86_64.whl"
+"mac_py_38_cpu $bucket/mac/cpu/tensorflow-${version}-cp38-cp38-macosx_10_14_x86_64.whl"
+"mac_py_39_cpu $bucket/mac/cpu/tensorflow-${version}-cp39-cp39-macosx_10_14_x86_64.whl"
+"mac_py_310_cpu $bucket/mac/cpu/tensorflow-${version}-cp310-cp310-macosx_10_14_x86_64.whl"
 )
 
 hashfile=binary-hashes.nix