diff --git a/Marlin/Conditionals.h b/Marlin/Conditionals.h
index 4a852dd221..3582170a62 100644
--- a/Marlin/Conditionals.h
+++ b/Marlin/Conditionals.h
@@ -90,11 +90,6 @@
 
   // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
   #ifdef LCD_I2C_PANELOLU2
-    // This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
-    // Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
-    // (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
-    // Note: The PANELOLU2 encoder click input can either be directly connected to a pin
-    //       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
     #define LCD_I2C_TYPE_MCP23017
     #define LCD_I2C_ADDRESS 0x20 // I2C Address of the port expander
     #define LCD_USE_I2C_BUZZER //comment out to disable buzzer on LCD
diff --git a/Marlin/Configuration.h b/Marlin/Configuration.h
index 47b2b91d0c..85865226a3 100644
--- a/Marlin/Configuration.h
+++ b/Marlin/Configuration.h
@@ -704,6 +704,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/configurator/config/Configuration.h b/Marlin/configurator/config/Configuration.h
index ecadfa17c9..497aac9f60 100644
--- a/Marlin/configurator/config/Configuration.h
+++ b/Marlin/configurator/config/Configuration.h
@@ -703,6 +703,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/Felix/Configuration.h b/Marlin/example_configurations/Felix/Configuration.h
index 9c4b5308de..2fc31d0f01 100644
--- a/Marlin/example_configurations/Felix/Configuration.h
+++ b/Marlin/example_configurations/Felix/Configuration.h
@@ -687,6 +687,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/Felix/Configuration_DUAL.h b/Marlin/example_configurations/Felix/Configuration_DUAL.h
index 00cb64aa21..d75109ac1e 100644
--- a/Marlin/example_configurations/Felix/Configuration_DUAL.h
+++ b/Marlin/example_configurations/Felix/Configuration_DUAL.h
@@ -641,6 +641,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/Hephestos/Configuration.h b/Marlin/example_configurations/Hephestos/Configuration.h
index b1f6f9a7a9..951c39a1d8 100644
--- a/Marlin/example_configurations/Hephestos/Configuration.h
+++ b/Marlin/example_configurations/Hephestos/Configuration.h
@@ -712,6 +712,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = true; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/K8200/Configuration.h b/Marlin/example_configurations/K8200/Configuration.h
index 964097aa77..abcc7e5e0f 100644
--- a/Marlin/example_configurations/K8200/Configuration.h
+++ b/Marlin/example_configurations/K8200/Configuration.h
@@ -720,6 +720,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/RepRapWorld/Megatronics/Configuration.h b/Marlin/example_configurations/RepRapWorld/Megatronics/Configuration.h
index e89f94b0d9..95596b5be3 100644
--- a/Marlin/example_configurations/RepRapWorld/Megatronics/Configuration.h
+++ b/Marlin/example_configurations/RepRapWorld/Megatronics/Configuration.h
@@ -704,6 +704,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/SCARA/Configuration.h b/Marlin/example_configurations/SCARA/Configuration.h
index 5d1bf57ebb..01d7f26137 100644
--- a/Marlin/example_configurations/SCARA/Configuration.h
+++ b/Marlin/example_configurations/SCARA/Configuration.h
@@ -745,6 +745,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/WITBOX/Configuration.h b/Marlin/example_configurations/WITBOX/Configuration.h
index 8fa07b0670..a29de26013 100644
--- a/Marlin/example_configurations/WITBOX/Configuration.h
+++ b/Marlin/example_configurations/WITBOX/Configuration.h
@@ -712,6 +712,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = true; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/adafruit/ST7565/Configuration.h b/Marlin/example_configurations/adafruit/ST7565/Configuration.h
index ed8d8811d0..35b2128c7b 100644
--- a/Marlin/example_configurations/adafruit/ST7565/Configuration.h
+++ b/Marlin/example_configurations/adafruit/ST7565/Configuration.h
@@ -703,6 +703,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/delta/biv2.5/Configuration.h b/Marlin/example_configurations/delta/biv2.5/Configuration.h
index 51047a61cc..a6a3859a6d 100644
--- a/Marlin/example_configurations/delta/biv2.5/Configuration.h
+++ b/Marlin/example_configurations/delta/biv2.5/Configuration.h
@@ -831,6 +831,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = true; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/delta/generic/Configuration.h b/Marlin/example_configurations/delta/generic/Configuration.h
index 98dfcb7e0b..bde2a9ddb2 100644
--- a/Marlin/example_configurations/delta/generic/Configuration.h
+++ b/Marlin/example_configurations/delta/generic/Configuration.h
@@ -831,6 +831,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = true; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/delta/kossel_mini/Configuration.h b/Marlin/example_configurations/delta/kossel_mini/Configuration.h
index 79b5baeb42..1fcc93db70 100644
--- a/Marlin/example_configurations/delta/kossel_mini/Configuration.h
+++ b/Marlin/example_configurations/delta/kossel_mini/Configuration.h
@@ -835,6 +835,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/delta/kossel_pro/Configuration.h b/Marlin/example_configurations/delta/kossel_pro/Configuration.h
index b500e621d1..902f9c24a6 100644
--- a/Marlin/example_configurations/delta/kossel_pro/Configuration.h
+++ b/Marlin/example_configurations/delta/kossel_pro/Configuration.h
@@ -858,6 +858,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/makibox/Configuration.h b/Marlin/example_configurations/makibox/Configuration.h
index 48c3fbc6a8..55024f4773 100644
--- a/Marlin/example_configurations/makibox/Configuration.h
+++ b/Marlin/example_configurations/makibox/Configuration.h
@@ -707,6 +707,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = false; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs
diff --git a/Marlin/example_configurations/tvrrug/Round2/Configuration.h b/Marlin/example_configurations/tvrrug/Round2/Configuration.h
index 6ba1d2d1aa..ec89f8105f 100644
--- a/Marlin/example_configurations/tvrrug/Round2/Configuration.h
+++ b/Marlin/example_configurations/tvrrug/Round2/Configuration.h
@@ -713,6 +713,12 @@ const bool Z_PROBE_ENDSTOP_INVERTING = true; // set to true to invert the logic
 //#define LCD_I2C_SAINSMART_YWROBOT
 
 // PANELOLU2 LCD with status LEDs, separate encoder and click inputs
+//
+// This uses the LiquidTWI2 library v1.2.3 or later ( https://github.com/lincomatic/LiquidTWI2 )
+// Make sure the LiquidTWI2 directory is placed in the Arduino or Sketchbook libraries subdirectory.
+// (v1.2.3 no longer requires you to define PANELOLU in the LiquidTWI2.h library header file)
+// Note: The PANELOLU2 encoder click input can either be directly connected to a pin
+//       (if BTN_ENC defined to != -1) or read through I2C (when BTN_ENC == -1).
 //#define LCD_I2C_PANELOLU2
 
 // Panucatt VIKI LCD with status LEDs, integrated click & L/R/U/P buttons, separate encoder inputs